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Mental Health Alliance


ZI-HUis a scientific network led by the Central Institute of Mental Health (ZI/CIMH), Germany’s largest psychiatric research institution, joined by longstanding collaborators from Heidelberg University, Ulm University and the German Cancer Research Center (DKFZ) with outstanding expertise in psychotherapy and global mental health, multi-omics and public mental health.


To improve mental health measurably and rapidly, we aim to translate a comprehensive account of mechanisms of mental health risk and protection into individualized therapy and prevention.


Learn more about our scientific excellence, the translational approach, the researchers and the projects.


Tang Y, Benusiglio D, Lefevre A, Hilfiger L, Althammer F, Bludau A, Hagiwara D, Baudon A, Darbon P, Schimmer J, Kirchner MK, Roy RK, Wang S, Eliava M, Wagner S, Oberhuber M, Conzelmann KK, Schwarz M, Stern JE, Leng G, Neumann ID, Charlet A, Grinevich V.

Social touch promotes interfemale communication via activation of parvocellular oxytocin neurons.

Nat Neurosci. 2020 Sep;23(9):1125-1137. doi: 10.1038/s41593-020-0674-y. Epub 2020 Jul 27.

PMID: 32719563

IF: 20.071

Bohus M, Kleindienst N, Hahn C, Müller-Engelmann M, Ludäscher P, Steil R, Fydrich T, Kuehner C, Resick PA, Stiglmayr C, Schmahl C, Priebe K.

Dialectical Behavior Therapy for Posttraumatic Stress Disorder (DBT-PTSD) Compared With Cognitive Processing Therapy (CPT) in Complex Presentations of PTSD in Women Survivors of Childhood Abuse: A Randomized Clinical Trial.

JAMA Psychiatry. 2020 Jul 22:e202148. doi: 10.1001/jamapsychiatry.2020.2148. Epub ahead of print.

PMID: 32697288

IF: 17.471

Reichert M, Schlegel S, Jagau F, Timm I, Wieland L, Ebner-Priemer UW, Hartmann A, Zeeck A.

Mood and Dysfunctional Cognitions Constitute Within-Subject Antecedents and Consequences of Exercise in Eating Disorders.

Psychother Psychosom. 2020;89(2):119-121. doi: 10.1159/000504061. Epub 2019 Nov 8.

PMID: 31707385

IF: 14.864


De Santis S, Cosa-Linan A, Garcia-Hernandez R, Dmytrenko L, Vargova L, Vorisek I, Stopponi S, Bach P, Kirsch P, Kiefer F, Ciccocioppo R, Sykova E, Moratal D, Sommer WH*, Canals S.

Chronic alcohol consumption alters extracellular space geometry and transmitter diffusion in the brain.

Sci Adv. 2020 Jun 24;6(26):eaba0154. doi: 10.1126/sciadv.aba0154.

*corresponding author

PMID: 32637601

IF: 13.116


Prof. Dr. Dr. h.c. Dr. h.c. Herta Flor, ZI, A mechanism-based approach to  the treatment of mental disorder: the example of chronic pain

Dr. Josef Frank, ZI, Epi-genome wide Association Studies: Clinical Examples, Challenges and Pitfalls

Prof. Dr. Christian Schaaf, Heidelberg University, Genetic complexity of neuropsychiatric disease – how to evaluate gene-disease relationships

Apl. Prof. Dr. Christian Wolf, Heidelberg University, Neural mechanisms of psychotic symptom formation: a domain-based approach

Prof. Dr. Daniel Durstewitz, Theoretical Neuroscience, ZI, Deep learning of dynamical systems for diagnosis, prognosis and intervention in psychiatry

Prof. Dr. Gerhard Gründer & Lea Mertens, Molecular Imaging, ZI, Propsychotherapeutic and psychedelic pharmacology: Towards a Center for Psychedelic and Consciousness Research at CIMH

PD Dr. Stephanie Bauer, University of Heidelberg, Digital interventions to enhance the reach, continuity, and outcome of mental healthcare

Apl. Prof. Dr. Jonas Tesarz, University of Heidelberg, Embodied trauma, ecological distress, and emerging early interventions

Prof. Dr. Valery Grinevich, Neuropeptides in Psychiatry, ZI: Novel oxytocin circuits and targets orchestrating socio-emotional behaviors

Prof. Dr. Uli Ebner-Priemer, Psychiatry and Psychotherapy, ZI & KIT: E-diaries and digital phenotyping to understand and predict psychopathology

Prof. Dr. Thomas Becker, Ulm/Günzburg: Understanding complex psychosocial interventions for people with severe mental illness

Prof. Dr. Prof. Dr. Stefan Reber, Psychosomatik, Ulm: A translational approach to understand, prevent and treat stress-associated disorders

Prof. Dr. Svenja Taubner, University of Heidelberg From neurobiology to treatment – the development of a therapeutic program for Conduct Disorder

Prof. Dr. Hans-Christoph Friederich, University of Heidelberg Mechanism of change in psychotherapy and its digital translation



Zentralinstitut für Seelische Gesundheit
J 5 • 68159 Mannheim


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